Wars keep on killing: Gulf War illness causes DNA damage in vets, according to new research

Post Traumatic Stress Disorder Soldier Shock Injury Helmet - Wars keep on killing: Gulf War illness causes DNA damage in vets, according to new research
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(Health News) Gulf War Illness (GWI), or Gulf War Syndrome, is the name given to a cluster of chronic symptoms affecting Gulf War veterans and civilian workers. The cause behind these symptoms — which range from fatigue to joint pains to memory problems — has been studied and debated on for the longest time. Yet scientists from Rutgers Medical School and the Veterans Affairs New Jersey Health Care System may have found an another potential answer, and lingering effect of this conflict; one that lies in mitochondrial DNA (mtDNA).

Post Traumatic Stress Disorder Soldier Shock Injury Helmet - Wars keep on killing: Gulf War illness causes DNA damage in vets, according to new research

According to lead researcher Michael J. Falvo, the idea for looking into the mitochondria came shortly after he joined the Veterans Affairs New Jersey Health Care System. There, he learned that numerous Gulf War veterans had unexplained symptoms throughout many areas of their bodies. “To me, that sounded awfully consistent with the symptoms of mitochondrial disorders. After reviewing the literature, I realized at that time there was no published study on GWI that investigated whether mitochondrial dysfunction contributed to symptoms,” explained Falvo.

As part of their study, Falvo and his colleagues recruited 28 participants: 21 veterans who had GWI, and three veterans without GWI, and four non-veterans who served as the control group. Blood samples were collected from each participant, which were then analyzed using a revolutionary technique that allowed the researchers to study the mtDNA without having to isolate it from total DNA.

They discovered that the veterans with GWI had more mtDNA and a greater number of lesions, implicating an overabundance of DNA damage. As stated on ScienceDaily.com, the lesions were direct measures of DNA damage, while the extra copies of mtDNA were reflections of the body’s response to the damage.

Their findings were consistent with the symptoms of patients who had mitochondrial dysfunction. People with this condition tend to experience a variety of symptoms across different organ systems, namely the muscles and nerves. Veterans who had GWI have reported feeling the same symptoms. Furthermore, there are veterans who claimed to have been exposed to dangerous chemicals and toxins during the war. (Related: Gulf War illness found to be caused by toxic chemicals.)

“Mitochondrial dysfunction among veterans with GWI may help explain, in part, the persistence of this illness for over 25 years. For example, chemical and environmental exposures during deployment may have provided the initial [harm] to mtDNA and accumulation of damage,” noted the researchers. Mitochondria, the energy powerhouses of cells, are highly sensitive to damage that could be caused by toxins.

Following this, Falvo has stated that he and his colleagues intend on expanding their efforts to further confirm the results of their study. “More importantly, we want to gain new knowledge of the damage of mtDNA on mitochondrial function and the recovery process. We need to be sure that our findings are robust. For us, that means confirming the present results but also investigating what might be contributing to mitochondrial DNA damage or its lack of repair,” he said.

Fast facts on Gulf War Illness

  • GWI is marked by a variety of chronic symptoms, with each affected person experiencing them differently. The most common ones are fatigue, musculoskeletal pain, cognitive problems, skin rashes, and diarrhea.
  • A 2013 report by the Institute of Medicine stated that one-third (roughly 175,000 to 250,000, or 25 to 35 percent) of Gulf War veterans have been impacted by this condition.
  • Past explanations for GWI have included psychological factors like post-traumatic stress disorder (PTSD); exposure to chemical warfare agents; other chemical agents such as smoke from oil well fires; and even depleted uranium.
  • Currently, there’s no known specific treatment for GWI, though one option suggested by research is cognitive-behavioral therapy, which is believed to help affected persons manage their symptoms.

Feel free to visit Medicine.news today for more stories focusing on health and well-being.

Sources include:

ScienceDaily.com

HopkinsMedicine.org

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My grandmother was a herbalist. She taught me how to mix herbs to cure ailments. I grew up with her from the age of 15 years old. I was going to school  and at the same time returned to her shop of herbs learning different kinds of mixture of herbs and also their names. I have been involved in herbal mixture and I also used it to cure a lot of people who orthodox medicine could not cure even though a lot of people have abused herbal medicine. Selling herbal mixture, popularly called agbo, has also been a great source of income to me and my family. Why I Started This Home Remedies Blog As an educated herbalist , i have been into these work for some years now which  I have help so many peoples. One good-day  i thought about people who are not benefit from these like those outside the Nigeria or peoples who are shame  to seek for a herbalist. Then i decides to create a website so as they can contact me and i would gladly help them. I began this blog in 2017 out of a desire to share my passion for herbs and natural living with others. Above all, am a Muslim and am thankful for the daily love and grace Allah bestows me. I’m glad you’ve visited me here at my home on the web and hope you will join me as I continue down the road to healthier living and my mission to help peoples across the nation! Let’s Connect I would love to connect with you!  Feel free to subscribe to receive free regular post updates in your inbox!  Also, you can find me on facebook, twitter,

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